Department Introduction

Toxicology | Our Speciality

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Excellence

When the poisoning occurs, the drug test plays an important role in the diagnosis and treatment and the understanding of the amount of intoxication is helpful to some extent to the clinical diagnosis and treatment.
 
Equipped with an UV/VIS Spectrophotometer, CP-3800 Gas Chromatography (GC), and GFAA-AA800 Graphite Furnace Absorption Spectrometry, the drug lab is the only poisoning test center in the central region. The center is currently providing intoxication testing services for pesticides, organic solvents, and heavy metals, and is scheduled to develop new testing items and offer public health consultation services.  
 

Pesticides
Pesticides are mainly used to kill insects and wild plants to cause crops to sprout or grow. The common types seen in the hospital are listed as follows:
 
Pesticide   Type   Description
Pesticides for killing insects   Organophosphorus, organic halides, carbamate, pyrethrum, etc.  
Most of the commodity names of organophosphorus pesticides are "XX松.”
Their main function is to consume cholinesterase, resulting in the accumulation of acetylcholine in the body and causing message transfer dysfunction in the systemic nervous system.

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In fact, organophosphorus pesticides contain at least two different types of organic compounds: one is organic phosphorus compounds and the other is organic solvents for dissolving organophosphorus insecticides, which mainly contain benzene, toluene or xylene. Not only organophosphorus compounds can cause poisoning, but the solvents in pesticides, such as benzene, toluene or xylene are also toxic.The center provides a test on hippuric acid (benzoylamide acid ester) for the determination of toluene poisoning.

Pesticides for killing weeds   Paraquat, Roundup, etc.   As many countries in the world (including Taiwan) have classified Paraquat as an illegal drug, all  Paraquat products on the market are derived from underground factories and illegal.
Pesticides for killing bacteria   Mostly metal-containing drugs, such as copper, arsenic, tin, and other preparations    
Organic solvents
According to their chemical structures, organic solvents can be divided into hydrocarbons, alcohols (e.g. organic solvents commonly used in isopropanol, antifreeze, dehydrators, and gasoline additives), ethers, ethanediol derivatives, ketones, esters, and halogenated hydrocarbons. 1) Acetone and trichloroethylene commonly used in the semiconductor industry; 2) organic solutions commonly used in the printing, coating, plastics, electronics, cell phone manufacturing, and other industries, including hexane, trichloroethylene, benzene (toluene), dichloroethane, and 3) well-known methanol (adulterated wine) are organic solvents, most of which have certain toxicity to the human body.  
 
Toluene is often used in the paint coating process within the building as a common diluent. Hippuric acid in the urine is the most commonly used biomarker for workers exposed to toluene.
 
Heavy metals
Metal refers to the metal with a relative atomic mass of more than 65. Thus, in the periodic table of elements, the metals after copper are heavy metals. Examples of heavy metal poisoning are mercury poisoning, lead poisoning, and so on.
 
Those with heavy metal poisoning or the manufacturers or sprayers in the metal industry, electroplating industry, welding industry, asphalt manufacturing, electronics manufacturing, battery manufacturing,  gemstone dyeing industry, pigment industry, paint industry, and pesticide industry.
 
The Division provides laboratory services for toxins such as As, Cd, Cr, Cu, Hg, Mn, Ni, PB, Zn, Al, etc.

 

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