醫師學術論文
Paper陳錦澤 Jin-Jer Chen 顧問
陳錦澤教授是心臟血管疾病專家,擅長一般內科疾病、心臟血管疾病、心律不整及高血壓等之診療,以及心臟超音波及心導管檢查。另曾任台大醫院內科教授、中央研究院生物醫學研究所研究員、公派沙烏地阿拉伯吉達法德國王醫院心臟科顧問醫師以及加拿大多倫多大學心臟科訪問教授。陳錦澤醫師在心臟血管疾病及分子生物學研究包括心臟肥大、心臟衰竭、動脈硬化及高血壓之分子機轉有深入研究並發表一百五十餘篇相關論文於國際知名期刊。
學術機構典藏
論文
期刊論文
期刊論文/Journal Paper (作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄) |
日期 | |
1 | (Ju-Chi Liu)、(Chun-Yao Cheng)、鄭志鴻(Cheng, Tzu-Hurng)、(Chen-Ning Liu)、陳錦澤(Jin-Jer Chen)、(Wen-Rui Hao)*,Unveiling the Potential: Remote Monitoring and Telemedicine in Shaping the Future of Heart Failure Management,Life-Basel,2024 Aug,14(8):1-10 | 2024 . 08 |
2 | (Wen-Rui Hao)、(Chun-Han Cheng)、(Ju-Chi Liu)、(Huan-Yuan Chen)、陳錦澤(Jin-Jer Chen)、鄭志鴻(Cheng, Tzu-Hurng)*,Understanding Galectin-3's Role in Diastolic Dysfunction: A Contemporary Perspective,Life-Basel,2024 Jul,14(7):1-19 | 2024 . 07 |
3 | (Hao, Wen-Rui)、(Cheng, Chun-Yao)、(Chen, Huan-Yuan)、陳錦澤(Jin-Jer Chen)、鄭志鴻(Cheng, Tzu-Hurng)*、(Liu, Ju-Chi)*,The Association Between Cafestol and Cardiovascular Diseases: A Comprehensive Review,Medicina-Lithuania,2024 Jun,60(6):1-12 | 2024 . 06 |
4 | (Hao, Wen Rui)、(Cheng, Chun Yao)、鄭志鴻(Cheng, Tzu-Hurng)*、(Liu, Ju Chi)*、(Wang, Yi Chih)*、陳錦澤(Jin-Jer Chen),Profiling of Differentially Expressed Circulating Exosomal Micrornas among Patients with Coronary Artery Disease,Diagnostic Pathology,2023 Nov,8(3):1000223-1-100022-9 | 2023 . 11 |
5 | (Wen-Rui Hao)、(Li-Chin Sung)、(Chun-Chao Chen)、洪宏杰*、(Ju-Chi Liu)*、陳錦澤(Jin-Jer Chen),Cafestol Activates Nuclear Factor Erythroid-2 Related Factor 2 and Inhibits Urotensin II-Induced Cardiomyocyte Hypertrophy,AMERICAN JOURNAL OF CHINESE MEDICINE,2019 Apr,57():30-38 | 2019 . 04 |
6 | (Wen-Rui Hao)、(Li-Chin Sung)、(Chun-Chao Chen)、陳柏源(Chen, Po-Yuan)*、鄭志鴻(Cheng, Tzu-Hurng)*、(Hung-Hsing Chao)*、(Ju-Chi Liu)*、陳錦澤(Jin-Jer Chen),Cafestol Inhibits Cyclic-Strain-Induced Interleukin-8, Intercellular Adhesion Molecule-1, and Monocyte Chemoattractant Protein-1 Production in Vascular Endothelial Cells,Oxidative Medicine and Cellular Longevity,2018 May,2018(7861518):1-10 | 2018 . 05 |
7 | (Hung-Hsing Chao)、陳柏源(Chen, Po-Yuan)、(Wen-Rui Hao)、(Wei-Ping Chiang)、鄭志鴻(Cheng, Tzu-Hurng)、(Shih-Hurng Loh)、梁育民(Leung, Yuk-Man)、(Ju-Chi Liu)、陳錦澤(Jin-Jer Chen)、(Li-Chin Sung)*,Lipopolysaccharide pretreatment increases protease-activated receptor-2 expression and monocyte chemoattractant protein-1 secretion in vascular endothelial cells,JOURNAL OF BIOMEDICAL SCIENCE,2017 Nov,2017(24):85 | 2017 . 11 |
8 | (Shaowei Zhuang)、鄭志鴻(CHENG, TZU-HURNG)、(Nang-Lang Shih)、(Ju-Chi Liu)、陳錦澤(Jin-Jer Chen)、洪宏杰(Hong, Hong-Jye)*、(Paul Chan),Tanshinone IIA induces heme oxygenase 1 expression and inhibits cyclic strain-induced interleukin 8 expression in vascular endothelial cells.,AMERICAN JOURNAL OF CHINESE MEDICINE,2016 Apr,44(2):377-388 | 2016 . 04 |
9 | (Hung-Hsing Chao)、洪宏杰(Hong, Hong-Jye)、鄭志鴻(CHENG, TZU-HURNG)、(Neng-Lang Shih)、(Shih-Hurng Loh)、(Ju-Chi Liu)、陳錦澤(Jin-Jer Chen)、(Li-Chin Sung)*,Nicorandil Inhibits Cyclic Strain-Induced Interleukin-8 Expression in Human Umbilical Vein Endothelial Cells,PHARMACOLOGY,2016 Apr,98():42-50 | 2016 . 04 |
10 | (Li-Chin Sung)、(Hung-Hsing Chao)、(Cheng-Hsien Chen)、(Jen-Chen Tsai)、(Ju-Chi Liu)、洪宏杰(Hong, Hong-Jye)*、鄭志鴻(CHENG, TZU-HURNG)*、陳錦澤(Jin-Jer Chen),Lycopene inhibits cyclic strain-induced endothelin-1 expression through the suppression of reactive oxygen species generation and induction of heme oxygenase-1 in heman umbilical vein endothelial cells,CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY,2015 Jun,42():632-639 | 2015 . 06 |
11 | (Hung-Hsing Chao)、宋立勤(Li-Chin Sung)、(Cheng-Hsien Chen)、(Ju-Chi Liu)、陳錦澤(Jin-Jer Chen)、鄭志鴻(CHENG, TZU-HURNG)*,Lycopene Inhibits Urotensin-II-Induced Cardiomyocyte Hypertrophy in Neonatal Rat Cardiomyocytes,Evidence-based Complementary and Alternative Medicine,2014 May,2014(724670):1-9 | 2014 . 05 |
12 | (Heng Lin)、(Hsiao-Fen Li)、(Hsi-Hsien Chen)、(Pei-Fang Lai)、(Shu-Hui Juan)、陳錦澤(Jin-Jer Chen)*、(Ching-Feng Cheng)*,Activating Transcription Factor 3 Protects against Pressure-Overload Heart Failure via the Autophagy Molecule Beclin-1 Pathway,MOLECULAR PHARMACOLOGY,2014 May,85(5):682-691 | 2014 . 05 |
13 | (Chung-Yi Lee)、(Yi-Tin Tsai)、(Shih-Hurng Loh)*、(Ju-Chi Liu)、(Tso-Hsiao Chen)、(Hung-Hsing Chao)*、鄭志鴻(CHENG, TZU-HURNG)*、陳錦澤(Jin-Jer Chen),Urotensin II Induces Interleukin 8 Expression in Human Umbilical Vein Endothelial Cells,PLoS One,2014 Feb,9(2):e90278-1-e90278-7 | 2014 . 02 |
14 | 洪宏杰(Hong, Hong-Jye)、劉如濟、陳柏源(Po-Yuan Chen)、陳錦澤(Jin-Jer Chen)、(Paul Chan)、鄭志鴻(CHENG, TZU-HURNG)*,Tanshinone IIA prevents doxorubicin-induced cardiomyocyte apoptosis through Akt-dependent pathway,International Journal of Cardiology,2012 May,157(2012):174-179 | 2012 . 05 |
15 | (Cho-Kai Wu)、(Chung-Yi Yang)、(Jou-Wei Lin)、(Hung-Jen Hsieh)、(Fu-Chun Chiu)、(Jen-Junn Chen)、(Jen-Kuang Lee)、(Shu-Wei Huang)、(Hung-Yuan Li)*、(Fu-Tien Chiang)、陳錦澤(Jin-Jer Chen)、(Chia-Ti Tsai),The Relationship Among Central Obesity,Systemic Inflammation, and Left Ventricular Diastolic Dysfunction as Determined by Structural Equation Modeling,Obesity,2012 Apr,20(4):730-737 | 2012 . 04 |
16 | (Yen-Ling Chen)、(Shih-Hurng Loh)、陳錦澤(Jin-Jer Chen)*、(Chien-Sung Tsai)*,Urotensin II prevents cardiomyocyte apoptosis induced by doxorubicin via Akt and ERK,European Journal of Pharmacology,2012 Feb,(680):88-94 | 2012 . 02 |
17 | 洪宏杰(Hong, Hong-Jye)、(Hsu FL)、蔡士彰(Shih-Chang Tsai)、(Lin CH)、劉如濟、陳錦澤(Jin-Jer Chen)、鄭志鴻(CHENG, TZU-HURNG)*、(Chan P)*,Tanshinone IIA attenuates cyclic strain-induced endothelin-1 expression in human umbilical vein endothelial cells.,CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY,2012 Jan,39(1):63-68 | 2012 . 01 |
18 | 趙洪興(Hung-Hsing Chao)、洪宏杰(Hong, Hong-Jye)、(Li-Chin Sung)、陳錦澤(Jin-Jer Chen)、鄭志鴻(CHENG, TZU-HURNG)*、劉如濟*,Nicorandil attenuates cyclic strain-induced endothelin-1 expression via the induction of activating transcription factor 3 in human umbilical vein endothelial cells,European Journal of Pharmacology,2011 Sep,667(1-3):292-297 | 2011 . 09 |
19 | (Cho-Kai Wu)、(Jen-Kuang Lee)、(Fu-Tien Chiang)、(Chic-Hsin Yang)、(Juey-Jen Hwang)、(Jiunn-Lee Lin)、(Chuen-Den Tseng)、陳錦澤(Jin-Jer Chen)*、(Chia-Ti Tsai),Plasma levels of TNF-a and IL-6 are associated with diastolic heart failure through downregulation of sarcoplasmic reticulum Ca2+ ATPase,CRITICAL CARE MEDICINE,2011 May,39(): | 2011 . 05 |
20 | (Wei-Shiung Lian)、(Winston Teng-Kuei Cheng)、(Chun-Chun Cheng)、(Felix Shih-Hsiang Hsiao)、陳錦澤(Jin-Jer Chen)、(Ching-Feng Cheng)*、(Shinn-Chih Wu)*,In vivo therapy of myocardial infarction with mesenchymal stem cells modified with prostaglandin I synthase gene improves cardiac performance in mice,LIFE SCIENCES,2011 Jan,88(9-10):455-464 | 2011 . 01 |
21 | 鄭志鴻(CHENG, TZU-HURNG)、(Jeremy Jan-Way Chen)、(Neng-Lang Shih)、(Jia-Wei Lin)、(Ju-Chi Liu)、(Yen-Ling Chen)、(Cheng-Hsien Chen)、陳錦澤(Jin-Jer Chen)*,MECHANICAL STRETCH INDUCES ENDOTHELIAL NITRIC OXIDE SYNTHASE GENE EXPRESSION IN NEONATAL RAT CARDIOMYOCYTES,CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY,2009 May,36(5-6):559-566 | 2009 . 05 |
22 | 鄭志鴻(CHENG, TZU-HURNG)、陳錦澤(Jin-Jer Chen)、(Cheng-Hsien Chen)、黃家樂(Kar-Lok Wong)*,Effects of propofol on cyclic strain-induced endothelin-1 expression in human umbilical vein endothelial cells,ANESTHESIOLOGY,2009 Jan,110(1):74-80 | 2009 . 01 |
23 | (Wu JS)、(Cheung WM)、(Tsai YS)、(Chen YE)、(Fong YE)、(Tsai HD)、(Chen YC)、(Liou JY)、(Shyue SK)、陳錦澤(Jin-Jer Chen)、(Y. Eugene Chen)、(Nobuyo Maeda)、(Kenneth K. Wu)、(Teng-Nan Lin),Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation.,CIRCULATION,2009 ,119(8):1124-1134 | 2009 . |
24 | (Yen-Ling Chen)、(Ju-Chi Liu)、(Shih-Hurng Loh)、(Cheng-Hsien Chen)、(Chuang-Ye Hong)、陳錦澤(Jin-Jer Chen)*、鄭志鴻(CHENG, TZU-HURNG)*,Involvement of reactive oxygen species in urotensin II-induced proliferation of cardiac fibroblasts.,European Journal of Pharmacology,2008 Sep,593(1-3):24-29 | 2008 . 09 |
25 | (Wen MS)、(Lee MTM)、陳錦澤(Jin-Jer Chen)、(Chuang HP)、(Lu LS)、(Chen CH)、(Lee TH)、(Kuo CT)、(Sun FM)、(Chang YJ),Prospective study of warfarin dosage requirements based on CYP2C9 and VKORC1 genotypes.,CLINICAL PHARMACOLOGY & THERAPEUTICS,2008 ,84(1):83-89 | 2008 . |
26 | (Dai DF)、(Thajeb P)、(Tu CF)、(Chiang FT)、(Chen CH)、(Yang RB)、陳錦澤(Jin-Jer Chen)*,Plasma concentration of SCUBE1, a novel platelet protein, is elevated in patients with acute coronary syndrome and ischemic stroke.,JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,2008 ,51(22):2173-2180 | 2008 . |
27 | (Chen CH)、鄭志鴻(CHENG, TZU-HURNG)、(Lin H)、(Shih NL)、(Chen YL)、(Chen SY)、(Cheng CF)、(Lian WS)、(Meng TC)、(Chiu WT)、陳錦澤(Jin-Jer Chen)*,Reactive oxygen species generation is involved in epidermal growth factor receptor transactivation through the transient oxidization of SHP-2 in endothelin-1 signaling pathway in rat cardiac fibroblasts.,MOLECULAR PHARMACOLOGY,2006 Apr,4(69):1347-1355 | 2006 . 04 |
28 | 鄭志鴻(CHENG, TZU-HURNG)、(Shih NL)、(Chen SY)、(Lin JW)、(Chen YL)、(Chen CH)、(Lin H)、(Cheng CF)、(Chiu WT)、(Wang DL)、陳錦澤(Jin-Jer Chen)*,Nitric oxide inhibits endothelin-1-induced cardiomyocyte hypertrophy through cGMP-mediated suppression of extracellular-signal regulated kinase phosphorylation.,MOLECULAR PHARMACOLOGY,2005 Oct,4(68):1183-1192 | 2005 . 10 |
29 | (Hsiang-Yu Yuan)、陳錦澤(Jin-Jer Chen)、(M.T. Michael Lee)、(Ju-Chieh Wung)、(Ying-Fu Chen)、(Min-Ji Charng)、(Ming-Jen Lu)、(Chi-Ren Hung)、(Chun-Yu Wei)、(Chien-Hsiun Chen),A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity,HUMAN MOLECULAR GENETICS,2005 Jul,14(13):1745-1751 | 2005 . 07 |
30 | 鄭志鴻(CHENG, TZU-HURNG)、(Chen CH)、(Lin H)、(Liu JC)、(Chao HH)、(Liou JY)、(Chen YL)、(Tsai HW)、(Chen YS)、(Cheng CF)、陳錦澤(Jin-Jer Chen)*,Role of mitogen-activated protein kinase pathway in reactive oxygen species-mediated endothelin-1-induced -myosin heavy chain gene expression and cardiomyocyte hypertrophy.,JOURNAL OF BIOMEDICAL SCIENCE,2005 ,1(12):123-133 | 2005 . |
研討會論文
研討會論文/Conference Papers (發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目) |
日期 | |
1 | FAR-INFRARED ATTENUATES CYCLIC STRAIN-INDUCED ENDOTHELIN-1 EXPRESSION VIA PI3K/AKT SIGNALING PATHWAY IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS,第七十八屆歐洲動脈硬化學會會議,德國 漢堡,2009.06.20~2009.06.23, | 2009 . 06 |
專書
暫無資料研究計畫
研究計畫/Research Grant (研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,計畫期間) |
日期 | |
1 | 整合型項下子計畫(主持人),BM107010220,,中研院,半乳糖凝集素 -1 和 3 在調控心臟重塑及心臟衰竭扮演不同的角色:臨床與基礎研究,2018.1.19~2018.6.30 | 2018 . 01 |
2 | 臨床試驗與研究計畫,CMUH105-REC1-071,何弘棋(Hung-Chi Ho),附醫廠商計畫,新藥 Antroquinonol在高膽固醇血症與高血脂症患者降脂療效的前瞻性雙盲隨機安慰劑對照的臨床試驗研究,2017.1.1~2017.12.31 | 2017 . 01 |
3 | 整合型項下子計畫(主持人),BM106010681,,中研院,半乳糖凝集素 -1 和 3 在調控心臟重塑及心臟衰竭扮演不同的角色:臨床與基礎研究,2017.1.25~2017.12.31 | 2017 . 01 |
4 | 臨床試驗與研究計畫,CMUH105-REC1-071,何弘棋(Hung-Chi Ho),附醫廠商計畫,新藥 Antroquinonol在高膽固醇血症與高血脂症患者降脂療效的前瞻性雙盲隨機安慰劑對照的臨床試驗研究,2016.1.1~2016.12.31 | 2016 . 01 |
5 | 個別型,BM104040480,,中研院,半乳糖苷結合凝集素-3,心肌纖維化以及舒張性心衰竭之機制探討研究,2015.4.14~2015.12.31 | 2015 . 04 |
6 | 個別型,DMR-103-002,鄭志鴻(CHENG, TZU-HURNG),附醫院內計畫,鑑定血液中之外吐小體微小核糖核酸對冠狀動脈側枝血管形成之角色,2013.8.1~2014.7.31 | 2013 . 08 |
7 | 個別型,NSC 102-2314-B-039 -001,鄭志鴻(CHENG, TZU-HURNG),科技部,半乳糖凝集素-3-調節心臟的纖維母細胞增生與心臟纖維化分子機制(2/2),2013.8.1~2014.7.31 | 2013 . 08 |
8 | 個別型,NSC 101-2314-B-039 -040 -,鄭志鴻(CHENG, TZU-HURNG),科技部,半乳糖凝集素-3-調節心臟的纖維母細胞增生與心臟纖維化分子機制(1/2),2012.8.1~2013.7.31 | 2012 . 08 |
專利技術
暫無資料獲獎事蹟
獲獎/Award (獲獎名稱,給獎單位,獲獎日期) |
日期 | |
1 | 第十八屆國家新創獎:臨床新創獎,財團法人生技醫療科技政策研究中心,2021.12.17 | 2021 . 12 |